Tofisopam is generally being accepted as a replacement for Etizolam. Tofisopam is an atypical benzodiazepine tranquilliser drug. It is currently used in Russia, Japan, and several European countries to treat various psychiatric conditions (mainly anxiety disorders). Several studies also suggests that Tofisopam does have antipsychotic effect. One of the biggest advantages of Tofisopam over conventional benzodiazepines is that it does not cause sedation and is not addictive, because of the structural differences. Tofisopam has unique chemical structure, which determines its pharmacological effects that are differs from that of other benzodiazepine tranquillisers. Tofisopam is not a GABA receptors agonist does not binds to benzodiazepine receptors. It is suggested that a possible target of action of 2,3-benzodiazepines is the opioid signal transduction. This suggestion is consistent with the results of animal studies, which shown that 2,3-BZDs potentiate the effects of opioid agonists, and their behavioural effects were inhibited by induced state of opioid tolerance. Besides having anxiolytic action, Tofisopam has mild stimulating effect. Studies suggest that Tofisopam increase the sensitivity of central dopamine receptors, as it is shown to potentiate the effects of dopaminergic stimulants. Shipping times for Tofisopam are 1 to 3 weeks normally and are sent tracked post. Shipping: 24h Dispatch with Fast – Global & USA Shipping | See details Guaranteed Delivery : Reship or Money Back Guarantee | See details

These tablets are the generic variant of Etizest, Etizex and Etilaam and come packaged in grip-seal bags. All of our tablets are pharmaceutical grade and contain the exact 1mg amount of Etizolam. https://go.drugbank.com/drugs/DB09166 Shipping times for Generic Etizolam are 1 to 3 weeks normally and are sent tracked post. Shipping: 24h Dispatch with Fast - Global & USA Shipping | See details Guaranteed Delivery : Reship or Money Back Guarantee | See details

Tapentadol is an opioid pain medication. An opioid is sometimes called a narcotic. Tapentadol is a prescription medicine that is used to treat moderate to severe pain. It binds to opioid receptors and other molecules in the central nervous system. Tapentadol hydrochloride is a type of opioid and a type of analgesic agent. When tapentadol is used for a long time, it may become habit-forming (causing mental or physical dependence). However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely. Information Links: https://www.sciencedirect.com/topics/medicine-and-dentistry/tapentadol Shipping times for Tapentadol are 1 to 3 weeks normally and are sent tracked post. 24h/48h Dispatch with Fast Global & USA Shipping | See details Guaranteed Delivery : Reship or Money Back Guarantee | See details